Learning and memory are vital for day-to-day living—from finding our way home to playing tennis to giving a cohesive speech. Some of us have personally witnessed the devastating consequences of memory disorders, whether it's the severe inability to form new memories, as seen in Alzheimer's patients, or difficulty in suppressing a recall of a memory of a highly unpleasant experience, as seen in PTSD patients. The main research interest in my laboratory is to decipher brain mechanisms subserving learning and memory. We seek to understand what happens in the brain when a memory is formed, when a fragile short-term memory is consolidated to a solid long-term memory, and when a memory formed previously is recalled on subsequent occasions. We also seek to understand the role of memory in decision-making, and how various external or internal factors, such as reward, punishment, attention and the subject's emotional state, affect learning and memory. In summary, we study how the central nervous system in the brain enables our mind, with a focus on learning and memory.
e
Press Releases


In the brain, timing is everything

Study reveals how the brain links memories of events that occur one after the other.  

Discovering hippocampal connections responsible for episodic memory

MIT neuroscientists map neural circuits involving the CA2 region of the hippocampus.  

Schizophrenia linked to abnormal brain waves

Neuroscientists discover neurological hyperactivity that produces disordered thinking.  

Neuroscientists plant false memories in the brain

The phenomenon of false memory has been well-documented: In many court cases, defendants have been found guilty based on testimony from witnesses and victims who were sure of their recollections, but DNA evidence later overturned the conviction... 

Researchers reverse Fragile X Syndrome symptoms in adult mice

Neuroscientists at MIT’s Picower Institute for Learning and Memory report in the March 18 Proceedings of the National Academy of Sciences (PNAS) that they have reversed autism symptoms in adult mice with a single dose of an experimental drug ... 

Researchers show that memories reside in specific brain cells

Our fond or fearful memories — that first kiss or a bump in the night — leave memory traces that we may conjure up in the remembrance of things past ... 

PICOWER: Neuron's distinct memory roles could point to new memory drugs

CAMBRIDGE, Mass. — Researchers at MIT’s Picower Institute for Learning and Memory report for the first time that neurons at different stages of their life cycles may perform two separate functions ... 

Picower researchers illuminate the gap between experience and association

CAMBRIDGE, Mass.--In the moments after lightning streaks through the sky, we wait for the clap of thunder that experience has ... 

MIT neuroscientists explain ‘Proustian effect’ of small details attached to big memories

CAMBRIDGE, Mass. – Neuroscientists at MIT’s Picower Institute of Learning and Memory have uncovered why relatively minor details of ... 

How past experiences inform future choices

Neuroscientists shed light on how past experiences subconsciously influence behavior CAMBRIDGE, Mass. — Researchers at MIT’s Picower Institute for ...