Jennie Young
Publications
| Title | Journal | Date | Authors |
| Metaplasticity of late-LTP: A critical role for PKA in synaptic tagging. | European Journal of Neuroscience. | 2006 | Young, J.Z. and Nguyen, P.V. |
| Homosynaptic and heterosynaptic inhibition of synaptic tagging and capture of long-term potentiation by previous synaptic activity. | Journal
of Neuroscience. 25(31):7221-31 |
2005 | Young, J.Z. and Nguyen, P.V. |
| Protein synthesis is required for the enhancement of hippocampal long-term potentiation and long-term memory by temporally spaced patterns of synaptic stimulation and behavioral training. | Journal
of Neurophysiology. 87(6):2770-7 |
2002 | Scharf M.T., Woo N.H., Lattal K.M., Young J.Z., Nguyen P.V., Abel T. |
| Differential maintenance and frequency-dependent tuning of LTP at hippocampal synapses of specific strains of inbred mice. | Journal of Neurophysiology. 84(5): 2484-93 | 2000 | Nguyen P.V., Duffy S.N., Young J.Z |
Poster Papers/Abstracts
| Title | Presentation | Date | Authors |
| A critical role for PKA in synaptic tagging and its regulation by prior synaptic activity. | 2nd Annual Neuron Satellite Meeting: Neurons & Memory, San Diego, CA, USA. CE-58 | 2004 | Young, J.Z. and Nguyen, P.V. |
| Heterosynaptic metaplasticity in the mouse hippocampus: Effects of prior low frequency activity on cAMP/PKA signaling and LTP. | Brain
Rehabilitation: Brain Plasticity and Learning Based Therapy, Torino,
Italy. |
2003 | Young, J.Z. and Nguyen, P.V. |
| Impaired long-term memory and deficient synaptic plasticity in transgenic mice expressing a constitutively active isoform of G-s-alpha. | Dr. Harold Atwood Satellite Symposium, CPS Winter Meeting 2002, Vernon, BC, Canada. | 2002 | Young, J.Z. and Nguyen, P.V. |
| Spaced training for fear conditioning and LTP recruits protein synthesis dependent processes. | Society for Neuroscience 31st Annual Meeting Abstracts, San Diego, CA, USA. 853.12 | 2001 | Scharf M.T., Woo N.H., Lattal K.M., Young J.Z., Nguyen P.V., Abel T. |
| Deficits in hippocampal cAMP-dependent synaptic facilitation may underlie defective hippocampus-based memory in specific strains of inbred mice | Society for Neuroscience 30th Annual Meeting Abstracts, New Orleans, LA, USA. 133.1 | 2000 | Duffy, S.N., Young, J.Z., Craddock K.J., Nguyen P.V. |
Presentations: |
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| How neurons encode their experiences. | Faculty of Graduate Studies and Research Forum, University of Alberta Open House, Edmonton, AB, Canada.* | 2004 | Young, J.Z. and Nguyen, P.V. |
| Homo- and hetero-synaptic inhibition of late phase-LTP by prior synaptic activity: Metaplastic effects on synaptic capture in mouse hippocampus CA1. | Canadian Society for Brain, Behaviour, and Cognitive Science 14th Annual Meeting, St. John’s, NL, Canada. | 2004 | Young, J.Z. and Nguyen, P.V. |
| Heterosynaptic effects of prior low frequency activity on hippocampal cAMP/PKA signalling and LTP. | Alberta Neuroscience Meeting 2003, Canmore, AB, Canada. | 2003 | Young, J.Z. and Nguyen, P.V. |
| Impaired long-term memory and deficient synaptic plasticity in transgenic mice expressing a constitutively active isoform of G-s-alpha. | Canadian Physiological Society Winter Meeting 2002, Vernon, BC, Canada. | 2002 | Young, J.Z. and Nguyen, P.V. |
Scholastic Achievements
| Dates | School | Degree | Concentration |
| 1999–
2005 |
Centre for
Neuroscience University of Alberta School of Medicine |
Ph.D. Neuroscience | Thesis Title: Critical Role for PKA in the Integration and Regulation of Multiple Synaptic Events in Hippocampal CA1 |
| Supervisor: Dr.
Peter V. Nguyen Department of Physiology and Centre for Neuroscience |
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| 1995–19 99 | Division of Neuroscience University of Alberta School of Medicine |
B.Sc. |
Thesis Title: Involvement
of Prejunctional Acetylcholine Receptors in the Decay of Facilitation at the Mouse Neuromuscular Junction |
| Supervisor:
Dr. William F. Dryden Department of Pharmacology and Centre for Neuroscience |
Contact Information
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Bldg. 46, Rm. 5295
Cambridge, MA 02139
(617) 253-8762