Impaired Hippocampal Representation of Space in CA-1 Specific NMDAR1 Knockout Mice

Cell, 87:1339-1349

1996

McHugh, T.J., Blum, K.I., Tsien, J.Z., Tonegawa, S., and Wilson, M.A.

Hippocampal CA-1-region-restricted Knockout of NMDAR1 Gene Disrupts Synaptic Plasticity, Place Fields, and Spatial Learning

Cold Spring Harbor Symp. Quant. Biol., 61: 225-238

1996

Tonegawa, S., Tsien, J.Z., McHugh, T.J., Huerta, P., Blum, K.I., and Wilson , M.A

NMDA receptors, place cells and hippocampal spatial memory

Nature Reviews Neuroscience. 5(5):361-372 

2004

 Nakazawa, K, McHugh, T.J., Wilson, M.A., and Tonegawa, S., and Wilson, M.A.

Multiple Electrode-Recording on the Genetically Engineered Mouse Brain (In Japanese) 

Genes & Medicine, 2(4): 47-53

1998 

McHugh, T.J. and Nakazawa, K

Analysis of Place Cell and EEG Activity in Acetylcholine Receptor M1 -/- Mice 

Soc. NeuroSci. Abstracts. 27

2001 

McHugh, T.J., Gerber, D.J., Tonegawa, S., and Wilson, M.A.

The Representation of Space is Impaired in CA-1 Specific NMDAR1 Knockout Mice

Soc. NeursoSci. Abstracts ,23: 501

1997 

 >Blum, K.I., McHugh, T.J., Tsien, J.Z., Tonegawa, S., and Wilson, M.A.

 
Characterization of Place Cell Activity in the Hippocampus of the Freely Behaving Mouse

Soc. NeursoSci. Abstracts, 22: 911 

1996 

McHugh, T.J. and Wilson, M.A

Summer 2001-
Present

Massachusetts Institute of Technology

Howard Hughes Medical Institute Postdoctoral Associate in the laboratory of Susumu Tonegawa.

Creating and analyzing region-specific transgenic mice for the study of learning and memory.

Fall 1994-
Summer 2001

Massachusetts Institute of Technology

Ph. D., Department of Biology
Advisor: Susumu Tonegawa

Thesis Title: “Application of Ensemble Recording and Conditional Genetics to the Mouse Hippocampus: A Study of Learning and Memory”

Fall 1990-Spring 1994

University of California, Berkeley

B.S. 1994

Molecular and Cell Biology